1. (+) i am late (-) (?) 2. (+) You are Busy (-) (?) 3. (+) he is in office (-) (?) 4. (+) She is a programmer (-) (?) 5. (+) it is ok (-) (?) 6. (+) We are

1.
(-) I am not late
(?) Am I late?
2.
You aren't busy
Are you busy?
3.
He isn't in the office
Is he in the office?
4.
She isn't a programmer
Is she a programmer?
5.
It isn't ok
Is it ok?
6.
We aren't ready
Are we ready?

1.
I am not late (-)
Am I late? (?)
2. You are not busy (-)
Are you busy? (?)
3.He is not in the office (-)
Is he in the office? (?)
4. 
She is not a programmer (-)
Is she a programmer? (?)
5. It is not ok (-)
Is it ok? (?)
6.We are not ready (-)
Are we ready? (?)